Rob Base, a rapper and one half of the Harlem hip-hop duo Rob Base & DJ E-Z Rock, has died after a battle with cancer. He was 59.

Axar.az reports, citing AP, Base, whose real name was Robert Ginyard, was best known for the 1988 chart-topper “It Takes Two,” a blend of hip-hop and house music that helped bring both genres into the mainstream.

“Rob’s music, energy, and legacy helped shape a generation and brought joy to millions around the world. Beyond the stage, he was a loving father, family man, friend, and creative force whose impact will never be forgotten,” read a statement on his Instagram announcing his death.