Louise Fletcher, who won an Academy Award for her role in the 1975 film One Flew Over the Cuckoo’s Nest, has died, aged 88.

Axar.az reports citing foreign media that Fletcher died in her sleep surrounded by family at her home in Montdurausse, France.

Andrew Bick, her son, told the Hollywood Reporter she died on Friday of natural causes. She had survived two bouts with breast cancer.

The actor won the Academy Award for best leading actress in 1976 for her portrayal of ruthless nurse Mildred Ratched in Miloš Forman’s adaptation of Ken Kesey’s 1962 novel of the same name. The movie also won awards for best picture, best director, best leading actor and best screenplay.